•
C a lc iu m a n d v ita m in D m a y b e ta k e n a t th e s a m e tim e
as E VISTA . It is im p o rta n t to take calciu m and v ita m in D, as
directed by y o u r physician , to p re v e n t o r treat o steo p o ro sis.
•
If y o u m is s a d o s e , ta k e it a s s o o n a s y o u r e m e m b e r .
H o w e v e r, if it is a lm o s t tim e fo r y o u r n ext d o s e , skip th e
m is s e d d o s e an d ta k e o n ly y o u r n e x t reg u larly s c h e d u le d
d o s e . D o n o t take tw o d o s e s a t th e s a m e tim e.
W h a t s h o u ld I a v o id w h ile ta k in g E V IS T A ?
•
B eing still fo r a lo n g tim e (s u c h a s d u rin g lo n g trip s o r
b ein g in bed after s u rg e ry ) can in c re a s e the risk o f b lo o d
clo ts. E V IS T A m a y a d d to th is risk. If y o u w ill n e e d to be
still fo r a lo n g tim e , ta lk w ith y o u r d o c to r a b o u t w a y s to
red u ce th e risk o f b lo o d clots. O n long trip s, m o v e a ro u n d
p eriodically. S to p ta k in g E V IS T A at least
3
d a y s b e fo re a
plan n ed s u rg e ry o r b e fo re y o u plan o n being still fo r a long
tim e . Y o u s h o u ld s ta r t ta k in g E V IS T A a g a in w h e n y o u
return to y o u r n o rm a l activities.
•
S o m e m e d ic in e s s h o u ld n o t b e ta k e n w ith E V IS T A (s e e
“ W h a t s h o u ld I te ll m y d o c to r b e fo re ta k in g E V IS T A ? ” ).
W h a t a re th e p o s s ib le s id e e ffe c ts of E V IS TA ?
S e rio u s a n d life -th r e a te n in g s id e e ffe c ts can o c c u r w h ile
ta k in g E V IS TA . T h e s e in c lu d e b lo o d clo ts a n d d ying fr o m stroke:
•
In c r e a s e d
r is k o f b lo o d c lo t s in th e le g s (d e e p v e in
th ro m b o s is ) a n d lu n g s (p u lm o n a ry e m b o lis m ) h ave been
reported w ith E VIS TA . W o m e n w h o have o r have had blood
c lo ts in th e legs, lu n g s, o r eye s s h o u ld n o t take E V IS T A .
•
W o m e n w h o h ave had a h e a rt a tta c k o r are at risk fo r a
h e a rt a tta c k m a y h a v e a n in c re a s e d ris k o f d y in g fr o m
stro ke w h e n ta k in g E V IS T A .
S e e “ W h a t is th e m o s t im p o r ta n t in fo rm a tio n I s h o u ld k n o w
a b o u t E V IS T A ? ”
T h e m o s t c o m m o n sid e e ffects of E V IS T A a re hot fla s h e s , leg
c ra m p s , s w e llin g o f th e feet, a n k le s , a n d le g s , flu s y n d r o m e ,
jo in t pain, a n d s w e a tin g . H o t fla s h e s are m o re c o m m o n d u rin g
th e firs t 6 m o n th s a fte r sta rtin g tre a tm e n t.
T h e s e are n o t all th e sid e effe c ts o f E V IS T A . Tell y o u r d o c to r
a b o u t a n y s id e e ffe c t th a t b o th e r s y o u o r th a t d o e s n o t g o
a w a y . If y o u h ave a n y p ro b le m s o r q u e s tio n s th at c o n c e rn y o u
w h i le ta k in g
E V IS T A , a s k y o u r d o c t o r o r p h a r m a c is t f o r
m o re in fo rm a tio n .
•
Y o u a re e n c o u r a g e d to r e p o rt n e g a t iv e s id e e ffe c ts of
prescription drugs to th e FD A . V isit w w w .ld a,g g v /m .e d w a tch ,
o r c a ll
1
-
8 0 0
-F D A -
1 0 8 8
.
W h a t e ls e s h o u ld I k n o w a b o u t E V IS T A ?
•
D o not use E V IS T A to p re v e n t h e a rt d isease, h e a rt attack,
o r strokes.
•
To g et th e c a lc iu m a n d v ita m in D y o u need, y o u r d o c to r
m a y a d v is e
y o u
to
c h a n g e
y o u r
d ie t a n d / o r
t a k e
s u p p le m e n ta l c a lc iu m a n d v ita m in D . Y o u r d o c to r m a y
s u g g e s t o th e r w a y s to help treat o r p re v e n t o s te o p o ro s is ,
in a d d itio n to ta k in g E V IS T A a n d g e ttin g the c a lc iu m a n d
v ita m in D y o u n eed. T h e s e m a y in c lu d e re g u la r exercise,
s to p p in g s m o k in g , a n d d rin k in g less alcohol.
•
W o m e n w h o h a v e h o t fla s h e s c a n ta k e E V IS T A . E V IS T A
d o e s n o t tre a t h o t fla s h e s , a n d it m a y cau se h o t fla s h e s in
s o m e w o m e n . (S e e “ W h a t a re th e p o s s ib le s id e e ffe c ts
of E V IS T A ? ” )
E V IS T A ® (ra lo x ife n e h y d ro c h lo rid e )
P V
3 1 2 4
A M P
•
E V IS T A has n o t b een fo u n d to c a u s e b re a s t te n d e rn e s s o r
e n la rg e m e n t. If y o u n o tic e a n y c h a n g e s in y o u r b reasts,
call y o u r d o c to r to fin d o u t th e c au se. B efo re startin g and
w h ile t a k in g
E V IS T A y o u s h o u ld
h a v e b r e a s t e x a m s
a n d m a m m o g r a m s , as d ire c te d by y o u r d o cto r. B ecau se
E V IS T A d o e s not e lim in a te th e c h a n c e of d e v e lo p in g breast
c a n c e rs ,
y o u
n e e d
th e s e
e x a m in a tio n s
to
fin d
a n y
b re a s t c a n c e rs as e a rly a s p ossib le.
•
E V IS T A s h o u ld n o t c a u s e s p o t tin g o r m e n s t r u a l- t y p e
b le e d in g . If y o u h a v e a n y v a g in a l b le e d in g , call y o u r d o c to r
to fin d o u t th e c a u s e . E V IS T A h a s n o t b e e n fo u n d to
in c re a s e th e risk fo r c a n c e r o f th e lining o f th e u teru s.
•
W o m e n in c lin ic a l tr ia ls h a v e ta k e n E V IS T A f o r u p to
e ig h t y ears.
H o w s h o u ld I s to re E V IS T A ?
•
S to re E V IS T A at 6 8 ° F to
7 7
°F (
2 0
° C -
2 5
°C ).
•
K e e p E V IS T A an d a ll m e d ic in e s out of the re ach
of c h ild r e n .
G e n e ra l In fo rm a tio n a b o u t th e s a fe a n d e ffe c tiv e u s e of EVISTA
M e d ic in e s are s o m e tim e s p re s c rib e d fo r p u rp o s e s o th e r th an
th e o n e s listed. D o not use E V IS T A fo r a c o n d itio n fo r w h ic h it
w a s n o t p re s c rib e d . D o n o t give y o u r E V IS T A to o th e r people,
even if th e y have the s a m e s y m p to m s y o u h ave. It m a y h a rm
th e m .
T h is is a s u m m a r y o f th e m o s t im p o rta n t in fo rm a tio n a b o u t
E V IS T A . If y o u w o u ld like m o re in fo rm a tio n a b o u t E V IS T A , talk
w ith y o u r d o c to r. Y ou can a s k y o u r d o c to r o r p h a rm a c is t fo r
in fo rm atio n a b o u t E VIS TA th a t is w ritten fo r health professionals.
For m o re in fo rm a tio n , call
1
-
8 0 0
-
5 4 5 - 5 9 7 9
(to ll-fre e ) o r go to
th e fo llo w in g w e b s ite : w w w .e v is ta .c o m .
* T h e b ra n d s listed a re tra d e m a rk s of th e ir re s p e c tiv e o w n e rs
a n d a re n o t tra d e m a rk s o f Eli Lilly a n d C o m p a n y . T h e m a k e rs of
th e s e b ra n d s are not affiliated w ith a n d d o n o t e n d o rs e Eli Lilly
a n d C o m p a n y o r its p ro d u cts.
L ite ra tu re issu ed S e p te m b e r
1 3 , 2 0 0 7
Eli L illy a n d C o m p a n y ,
In d ia n a p o lis , IN
4 6 2 8 5
, U S A
C o p y r ig h t©
1 9 9 7
,
2 0 0 7
, Eli Lilly and C om pan y. All rights reserved.
B ased on M ed ic a tio n G uide P V
3 1 2 4
A M P
P R IN T E D IN U S A
E V IS T A ® (ra lo x ife n e h y d ro c h lo rid e )
P V
3 1 2 4
A M P
